When asked when the downfall of humanity began, alien anthropologists all come to the release of a single piece of media:

Lotus 123

Which is hilarious, because you know it was put in there to “own the libs,” but instead these chucklefucks get it thrown back in their faces.

There have been a slew of Garfield edit parodies over the years. One of my favorites was one where the last panel was replaced by Garfield being thrown out a window. A few examples: